Second-half goals from Leroy Sane and Raheem Sterling stunned Arsenal at the Etihad Stadium on Sunday as Manchester City came from behind to win 2-1 and move seven points behind leaders Chelsea.
Chelsea's unbeaten start to the season ended with a dramatic 2-1 defeat at Newcastle United; Champions Manchester City took full advantage of Chelsea's surprise reverse to cut the gap at the top.
Lecister City's dynamic duo Jamie Vardy and Riyad Mahrez are not for sale at any price, manager Claudio Ranieri asserted after the pair combined again to fire their team back to the top of the Premier League.
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Manchester City claimed the win required to finally end Liverpool's relentless attempt to dethrone them as Premier League champions as they hit back from a goal down to crush Brighton and Hove Albion on the south coast on Sunday.
Many former players believe that storming out of games is a powerful tool to counter racism, a move that will force administrators to take the problem more seriously, and act in a way that compels clubs to obliterate such a culture and evict those responsible, says Dhruv Munjal.
Arsenal and Manchester City meet at The Emirates on Saturday when both teams will seek to roar into life after making spluttering starts to their Premier League campaigns.
News of all that's transpired on and off the football field
A week later than they would have preferred Manchester City were crowned Premier League champions on Sunday as second-placed Manchester United suffered a shock 1-0 home defeat by bottom club West Bromwich Albion.
Manchester City strengthened their Premier League top-four aspirations with a 5-0 thrashing of a woeful Crystal Palace side at the Etihad Stadium on Saturday.
Here are five talking points from the weekend's Premier League action:
Mohamed Salah struck four times in rampant Liverpool's 5-0 thrashing of Watford that lifted them back into third spot in the Premier League on Saturday.
IMAGES from the English Premier League matches played on Saturday
The fixture list suggests that Chelsea should still be able to finish above challengers Tottenham Hotspur. But strange things can happen when the pressure reaches it's greatest intensity and here was certainly something strange about Chelsea at Old Trafford on Sunday.
City, who have a 16-point lead, can win the Premier League title with a victory over Jose Mourinho's side at the Etihad Stadium on Saturday, but after their 3-0 loss to Liverpool in the Champions League on Wednesday, Guardiola said the players needed a lift.
Meet the men who shall face off against FIFA president Sepp Blatter
Manchester United striker Romelu Lukaku defended Jose Mourinho's confrontational style of management, saying that the Portuguese deserves respect for not hiding his true feelings like several Premier League bosses.
'It's like now with Lamela or Vertonghen, how you sit in the chair and cry because you miss someone... But the competition does not allow you to cry. You have to move on quick. It's a bit cruel, but you have to move on and try to win the next game'
Unbeaten Liverpool have 45 points from 17 games with champions Manchester City, who beat Everton 3-1 on Saturday, a point behind.
Images from the English Premier League matches played on Saturday
The victory takes Pep Guardiola's side into provisional second spot
The former Chelsea goalkeeper had to wait for 11 games to reach the landmark and produced an inspired performance that included a second-half penalty save from Watford striker Troy Deeney to help Arsenal seal the win.
Before Leicester enchanted the sporting world last year with their miraculous Premier League title win, Atletico had worked similar wonders in 2014 by breaking the strangehold of Real Madrid and Barcelona in La Liga.
In a TV interview before Tuesday's match between Manchester United and Everton at Old Trafford, Zlatan Ibrahimovic had been asked if he was the best striker in the Premier League.
When Jose Mourinho jumped to beleaguered Louis van Gaal's defence in February, sympathising that he should be given time.
Manchester City stumbled to the most unexpected defeat of the Premier League season on Saturday before neighbours Manchester United began their brave new world under Ole Gunnar Solskjaer with a glorious reminder of long-forgotten attacking swagger.
Chelsea ended their slump with a win over Arsenal while seemingly invincible Manchester City lost their 100 per cent record to West Ham United on a day of contrasting fortunes for the Premier League title favourites on Saturday.
City have 89 points, one more than rivals Liverpool, with both teams having three games to play -- and none of them against top six opponents.
Bristol City, from English football's second-tier, pulled off a sensation in the League Cup quarter-finals as they knocked out the holders Manchester United 2-1 amid late and wholly improbable drama at their Ashton Gate home on Wednesday.
The Premier League kicked off in unique fashion on Saturday as an own goal by Tottenham Hotspur's Kyle Walker gave Manchester United a 1-0 victory in an undistinguished season opener at Old Trafford.
England defender John Stones has been ruled out of their final two Euro 2016 qualifiers through injury, the FA said in a statement.
Manchester City beat Swansea 3-1 to make it a perfect 10 victories under Pep Guardiola, including six in the Premier League, as they recorded their best start to a top-flight campaign. City's victory was the perfect riposte to the Spaniard's old rival Jose Mourinho, who earlier saw his remodelled Manchester United sparkle without the dropped Wayne Rooney, thumping Premier League champions Leicester City 4-1. On a day of goals, both Manchester sides were outscored by Liverpool, who crushed Hull City 5-1 to take their tally to 24 in the past eight games.
Mario Balotelli will be available for Liverpool's home Premier League match against Aston Villa on Saturday after recovering from illness, manager Brendan Rodgers said.
Seasonal cheer has been scarce for Louis van Gaal after a six-match winless sequence for his Manchester United side intensified rumours that he will be sacked and Stoke City are unlikely to be offering any solace on Saturday.
Reigning champions Manchester City took the lead after 24 seconds but suffered a shock 2-1 defeat at Newcastle United.
The English Premier League resumed on Wednesday, after the forced break due to COVID-19. Here are IMAGES from the EPL matches played on Wednesday.
Summary of World Cup qualifiers played across the world on Thursday
Balotelli made his debut for his hometown club after completing a four-match suspension that he was handed at Olympique de Marseille last season, while the visitors were without Cristiano Ronaldo as he recovers from injury.
Chelsea put all their struggles away and looked like a renewed squad, stamping their class over Crystal Palace in their English Premier League match at the Selhurst Park on Sunday.
Frank Lampard could make an emotional appearance against former club Chelsea this weekend as his new employers Manchester City host Jose Mourinho's side in an early showdown between the Premier League's heavyweights. Catch all the action.